Complementary Syntheses Giving Access to a Full Suite of Differentially Substituted Phthalocyanine?Porphyrin Hybrids

Phthalocyanines and porphyrins are often the scaffolds of choice for use in widespread applications. Synthetic advances allow bespoke derivatives to be made, tailoring their properties. The selective synthesis unsymmetrical systems, particularly phthalocyanines, has remained a significant unmet challenge. Porphyrin-phthalocyanine hybrids offer potential combine favorable features both parent structures, but again synthetic strategies poorly developed. Here we demonstrate that give straightforward, controlled access differentially substituted meso-aryl-tetrabenzotriazaporphyrins by reaction between an aryl-aminoisoindolene (A) initiator complementary phthalonitrile (B). precursors conditions allows preparation 1:3 Ar-ABBB and, uniquely, 2:2 Ar-ABBA functionalized hybrids.